Huntington’s gene disrupts brain cells via changes to other genes

 

Huntington’s gene disrupts brain cells via changes to other genes

Huntington’s gene disrupts brain cells via changes to other genes.

Biological engineers at Massachusetts Institute of Technology (MIT) in the US have discovered that the gene that causes Huntington’s disease, a fatal neurodegenerative disorder, damages brain cell function by disrupting the on-off switching patterns of other genes. They hope the discovery will lead to ways of restoring normal gene expression that can be used in treatments to slow or stop the progression of the disease in its early stages.